Breeding reproductive ability of cows is a very complicated and extremely topical problem in livestock breeding today. The most important and critical period for animals’ health is the transition period. This is a transitional period which causes an imbalance in the neurohumoral system, metabolic and physiological changes that affect the further productivity of animals and their reproductive performance. Therefore, the aim of our research was to study the effect of Quatronan-Se preparation on the reproductive ability and biochemical parameters of blood of experimental cows. Experiments were conducted at "Svitanok" PF on cows of Ukrainian black-and-white milk breed. Was formed 2 groups – control and experimental, with 5 animals in each. In a control group of cows a physiological solution in the form of a stern was added to the main feed, in experimental – Quatronan-Se. Preparations were used in five days before the planned calving.According to the results of our research, it was found that in the experimental group after the use of the Quatronan-Se preparation, the duration of these indicators decreased by 54 days compared to the previous year. Analysis of changes in the metabolic profile of experimental animals shows that the indicators of cows of the experimental group after the use of Quatronan-Se preparation increased in the level of urea by 5,0%, and the concentration of total protein decreased by 2,6%, compared with the control group. In addition, the level of cholesterol of experimental animals decreased by 34,8% (p <0,01). It should also be noted that there is a 10% decrease in triglyceride levels compared with the control group. All the other indicators of biochemical status of animals had minor changes and corresponded to the physiological norm.Therefore, the use of Quatronan-Se in a dose of 10 ml in five days before the expected calving positively affects the course of calving itself, and the post-period; and stimulates reproductive performance
cows, Quatronan-Se, transition period, urea, milk production, enzymes